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The J-Glow™ is not a spa facial. It’s a physician-designed regenerative skin treatment that works at the cellular level combining your own platelet-rich plasma (PRP), micro-dosed botulinum toxin, and a clinical-grade anti-aging serum (peptides, hyaluronic acid, and vitamin C) into a single customised cocktail, then driving it deep into the dermis using microneedling-assisted transdermal delivery. Every layer of your skin receives the benefit simultaneously.
Developed and performed by Dr. J ABIM board-certified physician, 25+ years of clinical experience, 1,000+ five-star reviews the J-Glow™ is designed for patients in Orlando and the surrounding areas who want a meaningful, evidence-based improvement in skin quality: better radiance, firmer skin, smaller pores, reduced fine lines, improved texture, and a more even tone. The science behind each component of the J-Glow™ cocktail is published in peer-reviewed clinical literature, and you will receive an honest consultation before treatment so you understand what to realistically expect.
Total treatment time
Return same day
Fitzpatrick I–VI
Autologous PRP: Your own blood used
Same Day Visible glow
The defining feature of the J-Glow™ is its custom-compounded biological cocktail prepared fresh for each patient, in-clinic, on the day of treatment. It is not a pre-packaged product. Dr. J combines three distinct components, calibrated to your specific skin concerns:
A small blood draw (3–5 ml) is taken from your arm and centrifuged in-clinic to concentrate your own platelets. The resulting PRP contains growth factors VEGF, PDGF, TGF-beta, EGF, FGF at 5–10x their normal concentration in blood. These growth factors directly stimulate fibroblasts to produce new collagen and elastin, and accelerate dermal healing and remodelling. Because it is derived from your own blood, the risk of allergic reaction is negligible.
A highly diluted formulation of botulinum toxin A (Botox®, Dysport®, or Jeuveau®) used at a fraction of the concentration of standard aesthetic injections. At this micro-dose, the goal is not muscle paralysis but dermal-level skin quality improvement: pore size reduction, sebum control, and improvement in skin texture and fine lines. Published systematic reviews and clinical trials support intradermal micro-dosed BoNT-A as an effective modality for skin rejuvenation, separate from its neuromuscular applications.
A clinical-grade serum blend containing: signal peptides (to stimulate fibroblast activity and collagen gene expression), hyaluronic acid (a native skin molecule that binds water, restores dermal volume, and maintains structural integrity), and L-ascorbic acid / vitamin C (a potent antioxidant that promotes collagen biosynthesis, inhibits melanin formation, and neutralises UV-generated free radicals). These three actives work synergistically the peptides stimulate, the HA hydrates and supports, and vitamin C protects and brightens
Combining the three components into a single preparation allows all of them to be delivered simultaneously through the same microneedle channels maximising dermal penetration efficiency and minimising treatment time. More importantly, the components are biologically complementary: PRP growth factors stimulate cellular regeneration; peptides and HA support the dermal matrix the new cells produce; vitamin C protects against the oxidative stress that degrades collagen; and micro-dosed BoNT-A refines skin quality at the dermal level. Together, these four mechanisms address more dimensions of skin aging than any single ingredient can achieve alone.
Before anything touches your skin, Dr. J evaluates your Fitzpatrick skin type, photoaging grade (Glogau scale), sebaceous activity, active concerns, and medication history. This determines the needle depth, the cocktail ratio, and whether any component needs to be modified for your skin. For example, patients with active inflammatory acne, recent retinoid use, or compromised barrier function will have the protocol adjusted accordingly.
The face is thoroughly cleansed to remove all makeup, sunscreen, surface oils, and environmental debris. A professional double-cleanse is used the first pass removes surface contamination, the second prepares the skin. This is not a perfunctory step: introducing any surface contaminant through microneedle channels into the dermis carries infection risk, so clinical-grade cleansing and skin prep are non-negotiable.
The face is thoroughly cleansed to remove all makeup, sunscreen, surface oils, and environmental debris. A professional double-cleanse is used the first pass removes surface contamination, the second prepares the skin. This is not a perfunctory step: introducing any surface contaminant through microneedle channels into the dermis carries infection risk, so clinical-grade cleansing and skin prep are non-negotiable.
A physician-prescribed topical anaesthetic cream (typically EMLA or equivalent) is applied to the entire face and left on for 30 minutes under occlusion. This numbs the superficial skin layers effectively, making the microneedling step comfortable for virtually all patients. The 30-minute occlusion time is clinically important shorter application periods produce inadequate anaesthesia, particularly at the needle depths used for deeper dermal penetration. Patients are advised to relax during this time; many find it a welcome pause in the treatment.
While anaesthesia takes effect, Dr. J prepares your PRP. A small blood draw (approximately 3–5 ml) is taken from a peripheral vein the same amount as a routine blood test. The sample is centrifuged in-clinic using a calibrated protocol to separate plasma from red blood cells and concentrate the platelet layer. The resulting PRP is then combined with the anti-aging serum (peptides, HA, vitamin C) and a precisely calculated micro-dose of botulinum toxin A to create the final J-Glow™ cocktail. The preparation is made fresh for each patient, immediately before use. It is not stored, pre-made, or pooled.
Once anaesthesia is confirmed adequate, the J-Glow™ cocktail is applied to the skin surface and delivered into the dermis using a medical-grade microneedling device. The device creates thousands of precise, calibrated microchannels through the epidermis into the dermis simultaneously. Two things happen:
Needle depth, pass speed, and pressure are adjusted by Dr. J based on the treatment zone: deeper passes in thicker skin areas (cheeks, forehead), more conservative settings in the delicate periorbital and perioral zones.
Following microneedling, the skin barrier has been intentionally disrupted. A physician-selected calming serum, ceramide-based moisturiser, and SPF 30+ are applied to initiate repair and protect the newly open skin from UV and environmental exposure. Patients leave the clinic with calm, luminous skin. Transient redness similar in appearance to mild sunburn typically resolves within 2–6 hours. Downtime is minimal to none for the majority of patients.
Molecules like hyaluronic acid and growth factors are too large to penetrate intact skin in meaningful concentrations by topical application alone. Vitamin C at clinically effective concentrations (10–20%) is inherently unstable on the skin surface. Micro-dosed BoNT-A needs to reach the dermis to act on sebaceous glands and superficial muscle fibres. Microneedling solves all three problems simultaneously creating thousands of temporary microchannels that allow direct dermal access for all cocktail components, while simultaneously initiating collagen induction through the wound-healing response. A 2024 MDPI review of microneedling-assisted cosmetic delivery confirms that microneedle channels through the stratum corneum significantly enhance transdermal delivery of peptides, HA, vitamin C, PRP, and other macromolecules.
The J-Glow™ combines components that each have their own published clinical evidence base. The studies below were not funded by Dr. J Anti-Aging Clinic. Results represent group averages in research populations and do not constitute guarantees of individual outcomes. Skin response varies based on age, Fitzpatrick type, skin condition, and individual biology.
Citation: El-Domyati M et al. Int J Dermatol. 2018;57(11):1324-1334. PMID: 30105816
Design: 24 photoaged volunteers randomised into three groups: microneedling alone, microneedling + PRP, microneedling + 15% TCA peel. Six sessions at 2-week intervals. Both clinical and histological outcomes assessed.
Key Finding: Combining microneedling with PRP produced significantly better results than microneedling alone in wrinkle appearance and skin texture. Histological analysis confirmed new organised collagen bundle formation in all groups. PRP addition showed superior effect on dermal extracellular matrix compared to TCA peeling, with improved collagen fibre organisation and dermal density.
Relevance to J-Glow™: Directly validates the PRP + microneedling combination at the core of the J-Glow™ protocol, with both clinical improvement and histological collagen evidence.
Citation: J Cutan Aesthet Surg. 2023;16. PMC10833488. 16 clinical trials, 586 aggregate participants
Design: Narrative review of clinical trials (Jan 2017–Jul 2022) using PRP for facial skin rejuvenation, including monotherapy and combination protocols
Key Finding: PRP combined with other modalities (particularly microneedling) consistently outperformed PRP monotherapy. Histologically, PRP induced a growth factor cascade that increased dermal density, reduced wrinkles, and improved skin luminosity and hydration. PRP outperformed readymade growth factor solutions for patient satisfaction and longevity. The activated platelet secretome contains more than 300 bioactive proteins a synergistic complexity that commercial growth factor serums cannot replicate.
Relevance to J-Glow™: Supports both the use of autologous PRP and the rationale for combining it with other actives (as in the J-Glow™ cocktail) rather than using it in isolation.
Citation: Rahman E, Mosahebi A, et al. Plast Reconstr Surg Glob Open. 2024;12(8):e6084. PMID: 39185380
Design: PRISMA systematic review and meta-analysis. 10 studies (5 RCTs, 5 prospective cohort studies), 153 participants. Outcome measures: sebum production, pore size, skin hydration, skin texture, erythema, wrinkles, and facelift effect.
Key Finding: Studies consistently revealed positive effects of intradermal micro-dosed BoNT-A on facial rejuvenation outcomes including improvements in pore size, sebum production, skin texture, and fine lines. Effect is distinct from neuromuscular (muscle-relaxing) applications: intradermal BoNT-A acts on superficial dermis, sebaceous glands, and superficial muscle fibres without producing the visible movement restriction of standard aesthetic Botox.
Relevance to J-Glow™: Validates the inclusion of micro-dosed BoNT-A in the J-Glow™ cocktail as a skin quality agent specifically for pore reduction, sebum control, and surface texture improvement.
Citation: Ebrahim H, et al. J Clin Aesthet Dermatol. 2022;15(9):40-44. PMC9529074
Design: 42 patients. Split-face study: microneedling followed by topical BTX-A on one side; intradermal injection of BTX-A on the other side. Two sessions, 2 weeks apart.
Key Finding: Both microneedling-delivered and injected BTX-A produced effective outcomes with no statistically significant difference in efficacy (p=0.76). Patient satisfaction was higher on the microneedling side (81% very satisfied vs. 59.5% for injection side). The study confirms that microneedling-assisted delivery of BoNT-A achieves clinically equivalent dermal penetration to direct intradermal injection.
Relevance to J-Glow™: Directly validates using microneedling as the delivery mechanism for the BoNT-A component of the J-Glow™ cocktail showing both efficacy equivalence and superior patient satisfaction compared to injection.
Citation: Correia G, Magina S. J Cosmet Dermatol. 2023 Jul;22(7):1938-1945. PMID: 37128827
Design: Systematic review of 7 prospective RCTs (139 volunteers). Evaluated topical vitamin C for photoaging and melasma outcomes.
Key Finding: Topical vitamin C produced measurably smoother, less wrinkled skin vs. placebo in all three RCTs measuring surface topography. Objective assessments demonstrated significant skin lightening. The combination of vitamin C’s antioxidant, collagen-stimulating, and melanin-inhibiting properties makes it one of the most evidence-supported cosmeceutical actives in dermatology. Most effective at concentrations of 10–20% L-ascorbic acid.
Relevance to J-Glow™: Supports vitamin C as a core anti-aging serum component, especially relevant for Orlando patients with UV-driven photoaging. Microneedling delivery overcomes the penetration limitations of topical vitamin C.
Citation: MDPI Cosmetics. 2024;11(2):51. doi:10.3390/cosmetics11020051
Design: Comprehensive review of microneedling devices and fabricated microneedle patches in cosmetic delivery applications covering skin rejuvenation, scar treatment, hair loss, melasma, and drug delivery of ascorbic acid, hyaluronic acid, retinoids, niacinamide, peptides, and PRP.
Key Finding: Microneedle channels through the stratum corneum significantly enhance transdermal delivery of cosmetic agents including vitamin C, HA, peptides, and PRP growth factors enabling dermal concentrations that topical application alone cannot achieve. Collagen induction through the wound-healing cascade occurs independently of the delivered agent, providing an additive biological benefit. PRP combined with microneedling consistently outperformed microneedling with TCA in facial rejuvenation outcomes.
Relevance to J-Glow™: Establishes the mechanistic basis for using microneedling as the delivery vehicle for the entire J-Glow™ cocktail validating the approach of combining PRP, HA, vitamin C, peptides, and BoNT-A delivery through a single microneedling session.
The evidence base for PRP in facial rejuvenation is active and evolving. Some studies including a 2024 RCT (Pincelli et al., Plast Reconstr Surg Glob Open) found limited macroscopic improvement with injectable PRP alone in older women, suggesting that age, platelet quality, and delivery method significantly influence outcomes. The J-Glow™ uses PRP as one component of a multi-ingredient cocktail delivered via microneedling a protocol specifically supported by split-face studies showing superiority over monotherapy. Individual results will vary. Dr. J will give you an honest assessment of what is and is not achievable for your specific skin at consultation.
The J Lift™ is built on the most extensively studied injectable modalities in aesthetic medicine HA dermal fillers and botulinum toxin type A are among the most clinically validated cosmetic interventions available. The combination of these two modalities has been specifically studied and consistently outperforms either treatment used in isolation. Dr. J has designed the J Lift™ protocol in alignment with this evidence. The individual components and their combination have been evaluated in multiple peer-reviewed RCTs, multicenter clinical trials, and systematic reviews:
Dr. J reviews your complete health history and current medications before treatment to identify any contraindications or required protocol modifications.
What’s delivered to skin: PRP + BoNT-A + peptides + HA + vitamin C
Delivery mechanism: Microneedling direct dermal access
Autologous PRP: Yes your own blood, prepared in-clinic
Botox / BoNT-A component: Yes micro-dosed for skin quality
Collagen induction: Yes microneedling wound-healing cascade
Pore reduction: Yes BoNT-A targets sebaceous activity
Physician oversight: ABIM board-certified physician performs & supervises
Topical anaesthesia: Yes 30-min prescribed topical
Downtime: Minimal 2–6 hrs transient redness
What’s delivered to skin: Cosmetic-grade products, surface only
Delivery mechanism: Microneedling direct dermal access
Autologous PRP: No
Botox / BoNT-A component: No
Collagen induction: Mild only
Pore reduction: Temporary surface cleansing only
Physician oversight: Aesthetician only
Topical anaesthesia: Not required
Downtime: None
What’s delivered to skin: PRP only
Delivery mechanism: Microneedling or stamp
Autologous PRP: Yes
Botox / BoNT-A component: No
Collagen induction: Yes via microneedling
Pore reduction: Indirect via collagen remodelling
Physician oversight: Varies by provider
Topical anaesthesia: Varies by protocol
Downtime: Minimal 12–24 hrs pinkness
What’s delivered to skin: Proprietary serums, extraction
Delivery mechanism: Vacuum tip primarily surface/pore level
Autologous PRP: No
Botox / BoNT-A component: No
Collagen induction: No mechanical collagen induction
Pore reduction: Yes via extraction + suction
Physician oversight: Varies by clinic
Topical anaesthesia: Not required
Downtime: None to minima
They are related but different treatments. A Vampire Facial® combines PRP with microneedling. The J-Glow™ does that and more it adds micro-dosed botulinum toxin (for pore reduction, sebum control, and fine-line softening at the dermal level) plus a clinical-grade serum blend of peptides, hyaluronic acid, and vitamin C into the same cocktail. The J-Glow™ is Dr. J’s enhanced, physician-designed version that addresses more dimensions of skin quality in a single session than PRP + microneedling alone.
No. The BoNT-A used in the J-Glow™ cocktail is highly diluted a fraction of the dose used for standard aesthetic Botox. It is applied via microneedling to reach the superficial dermis, not injected into facial muscles. At this micro-dose and depth, it acts on sebaceous glands and superficial dermal fibres improving pore size, sebum control, and skin texture without producing any muscle paralysis or affecting facial movement. A published systematic review (PMC11343530, 2024) specifically confirms this distinction between intradermal micro-dosed BoNT-A and standard intramuscular BoNT-A applications.
Microneedling without anaesthesia is uncomfortable. With proper anaesthesia, most patients describe the J-Glow™ as easily tolerable. The 30-minute prescribed topical anaesthetic cream (typically EMLA or equivalent) numbs the superficial skin layers effectively before the procedure begins. You will feel mild pressure and warmth during treatment, but sharp pain is uncommon with adequate anaesthetic contact time. The 30-minute duration is clinically meaningful shorter contact times produce inadequate anaesthesia, which is why Dr. J prescribes physician-grade formulations rather than weaker over-the-counter products.
Most patients notice visible improvement in radiance and skin tone immediately after treatment, once the transient redness resolves (typically 2–6 hours). The deeper benefits new collagen synthesis, dermal remodelling, and pore tightening — develop progressively over 4–8 weeks as collagen production peaks. For long-term maintenance, most patients benefit from a series of 3 sessions spaced 4 weeks apart, followed by maintenance sessions every 2–3 months. Results from a complete series typically last 6–12 months. Individual results vary based on age, skin condition, sun exposure habits, and home skincare routine.
Downtime is minimal for the vast majority of patients. Transient redness similar to mild sunburn typically resolves within 2–6 hours of treatment. Some patients with sensitive skin or those who receive a more aggressive needle depth may experience mild pink/red tone lasting 12–24 hours. Pinpoint bruising is uncommon but possible in the periorbital area. Swelling is rarely significant. Makeup should be avoided for 12–24 hours. Normal activities can be resumed the same day but avoid strenuous exercise, saunas, swimming, and direct sun exposure for 24–48 hours.
The J-Glow™ is not appropriate for patients with active skin infections, open lesions, active inflammatory acne, isotretinoin use within 6 months, keloid scarring tendency, blood clotting disorders, anticoagulation therapy, known allergy to any cocktail component, or pregnancy/breastfeeding. A complete medical history review at consultation identifies any contraindications. If you are unsure whether you qualify, consultation will answer that question definitively without any obligation to proceed.
Yes and for many patients, combination scheduling produces the best overall outcomes. The J-Glow™ works particularly well as a companion to structural injectable treatments like the J Lift™ (HA fillers + BoNT-A + PDO threads): the J Lift™ addresses volume, structure, and dynamic wrinkles; the J-Glow™ addresses the skin quality that overlies that structural work. The two are typically spaced at least 2 weeks apart. The J-Glow™ also pairs well with IV therapy for systemic antioxidant support. Dr. J will design a combined treatment schedule if that is appropriate for your goals.
The J-Glow™ is available at Dr. J Anti-Aging Clinic in Orlando, FL. Your first consultation is complimentary. Dr. J will assess your skin, explain exactly what the treatment involves, and give you an honest picture of what results are realistically achievable for your specific skin. No pressure, no sales script.
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